Oral Streptococci Utilize a Siglec-Like Domain of Serine-Rich Repeat Adhesins to Preferentially Target Platelet Sialoglycans in Human Blood

Damaged cardiac valves attract blood-borne bacteria, and infective endocarditis is often caused by viridans group streptococci. While such bacteria use multiple adhesins to maintain their normal oral commensal state, recognition of platelet sialoglycans provides an intermediary for binding to damage...

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Foilsithe in:PLoS Pathog
Main Authors: Deng, Lingquan, Bensing, Barbara A., Thamadilok, Supaporn, Yu, Hai, Lau, Kam, Chen, Xi, Ruhl, Stefan, Sullam, Paul M., Varki, Ajit
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2014
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256463/
https://ncbi.nlm.nih.gov/pubmed/25474103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004540
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