Tandem sialoglycan-binding modules in a Streptococcus sanguinis serine-rich repeat adhesin create target dependent avidity effects

Sialic acid–binding immunoglobulin-like lectins (Siglec)–like domains of streptococcal serine-rich repeat (SRR) adhesins recognize sialylated glycans on human salivary, platelet, and plasma glycoproteins via a YTRY sequence motif. The SRR adhesin from Streptococcus sanguinis strain SK1 has tandem si...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Stubbs, Haley E., Bensing, Barbara A., Yamakawa, Izumi, Sharma, Pankaj, Yu, Hai, Chen, Xi, Sullam, Paul M., Iverson, T. M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Protein Structure and Folding
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586212/
https://ncbi.nlm.nih.gov/pubmed/32820052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014177
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