Oral Streptococci Utilize a Siglec-Like Domain of Serine-Rich Repeat Adhesins to Preferentially Target Platelet Sialoglycans in Human Blood

Damaged cardiac valves attract blood-borne bacteria, and infective endocarditis is often caused by viridans group streptococci. While such bacteria use multiple adhesins to maintain their normal oral commensal state, recognition of platelet sialoglycans provides an intermediary for binding to damage...

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Publicat a:PLoS Pathog
Autors principals: Deng, Lingquan, Bensing, Barbara A., Thamadilok, Supaporn, Yu, Hai, Lau, Kam, Chen, Xi, Ruhl, Stefan, Sullam, Paul M., Varki, Ajit
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256463/
https://ncbi.nlm.nih.gov/pubmed/25474103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004540
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