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Genetic Heterogeneity Beyond CYP2C8*3 Does Not Explain Differential Sensitivity to Paclitaxel-Induced Neuropathy

PURPOSE: The development of paclitaxel-induced peripheral neuropathy (PIPN) is influenced by drug exposure and patient genetics. The purpose of this analysis was to expand on a previous reported association of CYP2C8*3 and PIPN risk by investigating additional polymorphisms in CYP2C8 and in hundreds...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Main Authors: Hertz, Daniel L., Roy, Siddharth, Jack, John, Motsinger-Reif, Alison A., Drobish, Amy, Clark, L. Scott, Carey, Lisa A., Dees, E. Claire, McLeod, Howard L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256153/
https://ncbi.nlm.nih.gov/pubmed/24706167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-014-2910-1
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