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CYP2C8*3 predicts benefit/risk profile in breast cancer patients receiving neoadjuvant paclitaxel

Paclitaxel is one of the most frequently used chemotherapeutic agents for the treatment of breast cancer patients. Using a candidate gene approach, we hypothesized that polymorphisms in genes relevant to the metabolism and transport of paclitaxel are associated with treatment efficacy and toxicity....

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Autors principals: Hertz, Daniel L., Motsinger-Reif, Alison A., Drobish, Amy, Winham, Stacey J., McLeod, Howard L., Carey, Lisa A., Dees, E. Claire
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727245/
https://ncbi.nlm.nih.gov/pubmed/22527101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2054-0
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