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Reflections on the Catalytic Power of a TIM-Barrel
The TIM-barrel fold is described and its propagation throughout the enzyme universe noted. The functions of the individual front loops of the eponymous TIM-barrel of triosephosphate isomerase are presented in a discussion of: (a) Electrophilic catalysis, by amino acid side chains from loops 1 and 4,...
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| Publicat a: | Bioorg Chem |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4256097/ https://ncbi.nlm.nih.gov/pubmed/25092608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2014.07.001 |
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