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Nitrite binding to globins: linkage isomerism, EPR silence and reductive chemistry

The nitrite adducts of globins can potentially bind via O- or N- linkage to the heme iron. We have used EPR (electron paramagnetic resonance) and DFT (density functional theory) to explore these binding modes to myoglobin and hemoglobin. We demonstrate that the nitrite adducts of both globins have d...

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Bibliografische gegevens
Gepubliceerd in:Nitric Oxide
Hoofdauteurs: Silaghi-Dumitrescu, Radu, Svistunenko, Dimitri A., Cioloboc, Daniela, Bischin, Cristina, Scurtu, Florina, Cooper, Chris E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256065/
https://ncbi.nlm.nih.gov/pubmed/25172022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2014.08.007
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