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Evolution of the Division of Labor between Genes and Enzymes in the RNA World

The RNA world is a very likely interim stage of the evolution after the first replicators and before the advent of the genetic code and translated proteins. Ribozymes are known to be able to catalyze many reaction types, including cofactor-aided metabolic transformations. In a metabolically complex...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Main Authors: Boza, Gergely, Szilágyi, András, Kun, Ádám, Santos, Mauro, Szathmáry, Eörs
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256009/
https://ncbi.nlm.nih.gov/pubmed/25474573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003936
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