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Discovery of a Bacterial 5-Methylcytosine Deaminase

[Image: see text] 5-Methylcytosine is found in all domains of life, but the bacterial cytosine deaminase from Escherichia coli (CodA) will not accept 5-methylcytosine as a substrate. Since significant amounts of 5-methylcytosine are produced in both prokaryotes and eukaryotes, this compound must eve...

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Publicat a:Biochemistry
Autors principals: Hitchcock, Daniel S., Fedorov, Alexander A., Fedorov, Elena V., Almo, Steven C., Raushel, Frank M.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255641/
https://ncbi.nlm.nih.gov/pubmed/25384249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5012767
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