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Non-Canonical Notch Signaling in Cancer and Immunity
Canonical Notch signaling is initiated by γ-secretase-mediated cleavage of the Notch receptor, leading to the release of the active intra-cellular domain of Notch that migrates to the nucleus and interacts with RBP-Jκ, resulting in the activation of downstream target genes. While canonical Notch sig...
में बचाया:
| में प्रकाशित: | Front Oncol |
|---|---|
| मुख्य लेखकों: | , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Frontiers Media S.A.
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4255497/ https://ncbi.nlm.nih.gov/pubmed/25538890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00345 |
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