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Systems Mechanobiology: Tension-Inhibited Protein Turnover Is Sufficient to Physically Control Gene Circuits

Mechanotransduction pathways convert forces that stress and strain structures within cells into gene expression levels that impact development, homeostasis, and disease. The levels of some key structural proteins in the nucleus, cytoskeleton, or extracellular matrix have been recently reported to sc...

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Publicat a:Biophys J
Autors principals: Dingal, P.C. Dave P., Discher, Dennis E.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255197/
https://ncbi.nlm.nih.gov/pubmed/25468352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.10.042
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