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Systems Mechanobiology: Tension-Inhibited Protein Turnover Is Sufficient to Physically Control Gene Circuits

Mechanotransduction pathways convert forces that stress and strain structures within cells into gene expression levels that impact development, homeostasis, and disease. The levels of some key structural proteins in the nucleus, cytoskeleton, or extracellular matrix have been recently reported to sc...

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Dettagli Bibliografici
Pubblicato in:Biophys J
Autori principali: Dingal, P.C. Dave P., Discher, Dennis E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255197/
https://ncbi.nlm.nih.gov/pubmed/25468352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.10.042
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