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Systems Mechanobiology: Tension-Inhibited Protein Turnover Is Sufficient to Physically Control Gene Circuits

Mechanotransduction pathways convert forces that stress and strain structures within cells into gene expression levels that impact development, homeostasis, and disease. The levels of some key structural proteins in the nucleus, cytoskeleton, or extracellular matrix have been recently reported to sc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biophys J
Prif Awduron: Dingal, P.C. Dave P., Discher, Dennis E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255197/
https://ncbi.nlm.nih.gov/pubmed/25468352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.10.042
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