Leptin Therapy Alters Appetite and Neural Responses to Food Stimuli in Brain Areas of Leptin-Sensitive Subjects Without Altering Brain Structure

CONTEXT: Leptin is a key regulator of energy intake and expenditure. Individuals with congenital leptin deficiency demonstrate structural and functional brain changes when given leptin. However, whether acquired leptin deficiency may operate similarly is unclear. OBJECTIVE: We set out to determine w...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Farr, Olivia M., Fiorenza, Christina, Papageorgiou, Panagiotis, Brinkoetter, Mary, Ziemke, Florencia, Koo, Bang-Bon, Rojas, Rafael, Mantzoros, Christos S.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
Assuntos:
Hot Topics in Translational Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255115/
https://ncbi.nlm.nih.gov/pubmed/25279500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-2774
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