Leptin and Amylin Act in an Additive Manner to Activate Overlapping Signaling Pathways in Peripheral Tissues: In vitro and ex vivo studies in humans

OBJECTIVE: Amylin interacts with leptin to alter metabolism. We evaluated, for the first time, amylin- and/or leptin-activated signaling pathways in human peripheral tissues (hPTs). RESEARCH DESIGN AND METHODS: Leptin and amylin signaling studies were performed in vitro in human primary adipocytes (...

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Autori principali: Moon, Hyun-Seuk, Chamberland, John P., Diakopoulos, Kalliope N., Fiorenza, Christina G., Ziemke, Florencia, Schneider, Benjamin, Mantzoros, Christos S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2011
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005478/
https://ncbi.nlm.nih.gov/pubmed/20870968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc10-0518
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