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Amylin and leptin activate overlapping signalling pathways in an additive manner in mouse GT1-7 hypothalamic, C(2)C(12) muscle and AML12 liver cell lines
AIMS/HYPOTHESIS: It has been suggested that amylin amplifies leptin’s effects and affects energy homeostasis synergistically with leptin in animals and humans. However, no previous study has reported on amylin and leptin signalling in hypothalamic, muscle and liver cells. METHODS: Leptin and amylin...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3780406/ https://ncbi.nlm.nih.gov/pubmed/21997794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-011-2332-0 |
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