GAIP Interacting Protein C-Terminus Regulates Autophagy and Exosome Biogenesis of Pancreatic Cancer through Metabolic Pathways

GAIP interacting protein C terminus (GIPC) is known to play an important role in a variety of physiological and disease states. In the present study, we have identified a novel role for GIPC as a master regulator of autophagy and the exocytotic pathways in cancer. We show that depletion of GIPC-indu...

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Veröffentlicht in:PLoS One
Hauptverfasser: Bhattacharya, Santanu, Pal, Krishnendu, Sharma, Anil K., Dutta, Shamit K., Lau, Julie S., Yan, Irene K., Wang, Enfeng, Elkhanany, Ahmed, Alkharfy, Khalid M., Sanyal, Arunik, Patel, Tushar C., Chari, Suresh T., Spaller, Mark R., Mukhopadhyay, Debabrata
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255029/
https://ncbi.nlm.nih.gov/pubmed/25469510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114409
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