GAIP Interacting Protein C-Terminus Regulates Autophagy and Exosome Biogenesis of Pancreatic Cancer through Metabolic Pathways

GAIP interacting protein C terminus (GIPC) is known to play an important role in a variety of physiological and disease states. In the present study, we have identified a novel role for GIPC as a master regulator of autophagy and the exocytotic pathways in cancer. We show that depletion of GIPC-indu...

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Publicado en:PLoS One
Main Authors: Bhattacharya, Santanu, Pal, Krishnendu, Sharma, Anil K., Dutta, Shamit K., Lau, Julie S., Yan, Irene K., Wang, Enfeng, Elkhanany, Ahmed, Alkharfy, Khalid M., Sanyal, Arunik, Patel, Tushar C., Chari, Suresh T., Spaller, Mark R., Mukhopadhyay, Debabrata
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255029/
https://ncbi.nlm.nih.gov/pubmed/25469510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114409
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