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Antiviral Interferon-Beta Signaling Induced by Designed Transcription Activator-Like Effectors (TALE)
Here we show that designed transcription activator-like effectors (TALEs) that bind to defined areas of the interferon beta promoter are capable to induce IFN-beta expression and signaling in human cells. Importantly, TALE-mediated IFN-beta signaling occurs independently of pathogen pattern recognit...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4255017/ https://ncbi.nlm.nih.gov/pubmed/25470486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114288 |
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