Prognostic Value of Elevated Levels of Intestinal Microbe-Generated Metabolite Trimethylamine-N-oxide in Patients with Heart Failure: Refining the Gut Hypothesis

BACKGROUND: Altered intestinal function is prevalent in patients with heart failure (HF), but its role in adverse outcomes is unclear. OBJECTIVE: This study investigated the potential pathophysiologic contributions of intestinal microbiota in HF. METHODS: We examined the relationship between fasting...

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Udgivet i:J Am Coll Cardiol
Main Authors: Wilson Tang, W. H., Wang, Zeneng, Fan, Yiying, Levison, Bruce, Hazen, Jennie E., Donahue, Lillian M., Wu, Yuping, Hazen, Stanley L.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254529/
https://ncbi.nlm.nih.gov/pubmed/25444145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2014.02.617
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