Choline Diet and Its Gut Microbe Derived Metabolite, Trimethylamine N-Oxide (TMAO), Exacerbate Pressure Overload-Induced Heart Failure

BACKGROUND: Trimethylamine N-oxide (TMAO), a gut microbe dependent metabolite of dietary choline and other trimethylamine containing nutrients, is both elevated in the circulation of patients suffering from heart failure (HF) and heralds worse overall prognosis. In animal studies, dietary choline or...

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Gepubliceerd in:Circ Heart Fail
Hoofdauteurs: Organ, Chelsea L., Otsuka, Hiroyuki, Bhushan, Shashi, Wang, Zeneng, Bradley, Jessica, Trivedi, Rishi, Polhemus, David J., Tang, W. H. Wilson, Wu, Yuping, Hazen, Stanley L., Lefer, David J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943035/
https://ncbi.nlm.nih.gov/pubmed/26699388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.115.002314
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