Choline Diet and Its Gut Microbe Derived Metabolite, Trimethylamine N-Oxide (TMAO), Exacerbate Pressure Overload-Induced Heart Failure

BACKGROUND: Trimethylamine N-oxide (TMAO), a gut microbe dependent metabolite of dietary choline and other trimethylamine containing nutrients, is both elevated in the circulation of patients suffering from heart failure (HF) and heralds worse overall prognosis. In animal studies, dietary choline or...

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Publicado en:Circ Heart Fail
Autores principales: Organ, Chelsea L., Otsuka, Hiroyuki, Bhushan, Shashi, Wang, Zeneng, Bradley, Jessica, Trivedi, Rishi, Polhemus, David J., Tang, W. H. Wilson, Wu, Yuping, Hazen, Stanley L., Lefer, David J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943035/
https://ncbi.nlm.nih.gov/pubmed/26699388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.115.002314
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