AURKA regulates JAK2–STAT3 activity in human gastric and esophageal cancers

Aurora kinase A is a frequently amplified and overexpressed gene in upper gastrointestinal adenocarcinomas (UGCs). Using in vitro cell models of UGCs, we investigated whether AURKA can regulate Signal Transducer and Activator of Transcription 3 (STAT3). Our data indicate that overexpression of AURKA...

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Publicat a:Mol Oncol
Autors principals: Katsha, Ahmed, Arras, Janet, Soutto, Mohammed, Belkhiri, Abbes, El-Rifai, Wael
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2014
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254172/
https://ncbi.nlm.nih.gov/pubmed/24953013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.05.012
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