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Expanding the results of a high throughput screen against an isochorismate-pyruvate lyase to enzymes of a similar scaffold or mechanism
Antibiotic resistance is a growing health concern, and new avenues of antimicrobial drug design are being actively sought. One suggested pathway to be targeted for inhibitor design is that of iron scavenging through siderophores. Here we present a high throughput screen to the isochorismate-pyruvate...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Bioorg Med Chem |
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Κύριοι συγγραφείς: | , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
2014
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4254016/ https://ncbi.nlm.nih.gov/pubmed/25282647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.09.010 |
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