Hypocholesterolemic effects of mevinolin in patients with heterozygous familial hypercholesterolemia.
We have evaluated the hypolipidemic effects of mevinolin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme in cholesterol biosynthesis in 13 patients with heterozygous familial hypercholesterolemia (FH). Patients were maintained on a low-cholestero...
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| Publicado no: | J Clin Invest |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1984
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425384/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6569064/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111618 |
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