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Hypocholesterolemic effects of mevinolin in patients with heterozygous familial hypercholesterolemia.

We have evaluated the hypolipidemic effects of mevinolin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme in cholesterol biosynthesis in 13 patients with heterozygous familial hypercholesterolemia (FH). Patients were maintained on a low-cholestero...

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Detalles Bibliográficos
Main Authors: Illingworth, D R, Sexton, G J
Formato: Artigo
Idioma:Inglês
Publicado: 1984
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC425384/
https://ncbi.nlm.nih.gov/pubmed/6569064
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