Hypocholesterolemic effects of mevinolin in patients with heterozygous familial hypercholesterolemia.

We have evaluated the hypolipidemic effects of mevinolin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme in cholesterol biosynthesis in 13 patients with heterozygous familial hypercholesterolemia (FH). Patients were maintained on a low-cholestero...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Illingworth, D R, Sexton, G J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1984
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425384/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6569064/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111618
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