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Structure of a partially unfolded form of Escherichia coli dihydrofolate reductase provides insight into its folding pathway

Proteins frequently fold via folding intermediates that correspond to local minima on the conformational energy landscape. Probing the structure of the partially unfolded forms in equilibrium under native conditions can provide insight into the properties of folding intermediates. To elucidate the s...

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Vydáno v:Protein Sci
Hlavní autoři: Kasper, Joseph R, Liu, Pei-Fen, Park, Chiwook
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253813/
https://ncbi.nlm.nih.gov/pubmed/25252157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2555
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