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Structure of a partially unfolded form of Escherichia coli dihydrofolate reductase provides insight into its folding pathway

Proteins frequently fold via folding intermediates that correspond to local minima on the conformational energy landscape. Probing the structure of the partially unfolded forms in equilibrium under native conditions can provide insight into the properties of folding intermediates. To elucidate the s...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Kasper, Joseph R, Liu, Pei-Fen, Park, Chiwook
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253813/
https://ncbi.nlm.nih.gov/pubmed/25252157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2555
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