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The expanding role for chromatin and transcription in polyglutamine disease

Nine genetic diseases arise from expansion of CAG repeats in seemingly unrelated genes. They are referred to as polyglutamine (polyQ) diseases due to the presence of elongated glutamine tracts in the corresponding proteins. The pathologic consequences of polyQ expansion include progressive spinal, c...

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Dades bibliogràfiques
Publicat a:Curr Opin Genet Dev
Autors principals: Mohan, Ryan D., Abmayr, Susan M., Workman, Jerry L.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253674/
https://ncbi.nlm.nih.gov/pubmed/25108806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2014.06.008
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