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The expanding role for chromatin and transcription in polyglutamine disease
Nine genetic diseases arise from expansion of CAG repeats in seemingly unrelated genes. They are referred to as polyglutamine (polyQ) diseases due to the presence of elongated glutamine tracts in the corresponding proteins. The pathologic consequences of polyQ expansion include progressive spinal, c...
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| 發表在: | Curr Opin Genet Dev |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4253674/ https://ncbi.nlm.nih.gov/pubmed/25108806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2014.06.008 |
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