טוען...
Removal of a small C-terminal region of JCV and SV40 large T antigens has differential effects on transformation
The large T antigen (LT) protein of JCV and SV40 polyomaviruses is required to induce tumors in rodents and transform cells in culture. When both LTs are compared side-by-side in cell culture assays, SV40 shows a more robust transformation phenotype even though the LT sequences are highly conserved....
שמור ב:
| הוצא לאור ב: | Virology |
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| Main Authors: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4253650/ https://ncbi.nlm.nih.gov/pubmed/25129438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.07.038 |
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