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SV40 Large T antigen induces ISGs through ATR Kinase

Polyomaviruses encode a Large T antigen (LT), a multifunctional protein essential for the regulation of both viral and host cell gene expression and productive viral infection. Previously, we have shown that stable expression of LT protein results in upregulation of genes involved in the interferon...

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Detalhes bibliográficos
Main Authors: Forero, Adriana, Giacobbi, Nicholas S., McCormick, Kevin D., Gjoerup, Ole V., Bakkenist, Christopher J., Pipas, James M., Sarkar, Saumendra N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078001/
https://ncbi.nlm.nih.gov/pubmed/24799566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303470
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