The tumor promoting activity of the EP4 receptor for prostaglandin E(2) in murine skin

To determine whether the EP4 receptor for prostaglandin E(2) (PGE(2)) contributes to the tumor promoting activity of PGs in murine skin, EP4 over‐expressing mice (BK5.EP4) were generated and subjected carcinogenesis protocols. An initiation/promotion protocol resulted in 25‐fold more squamous cell c...

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Veröffentlicht in:Mol Oncol
Hauptverfasser: Simper, Melissa S., Rundhaug, Joyce E., Mikulec, Carol, Bowen, Rebecca, Shen, Jianjun, Lu, Yue, Lin, Kevin, Surh, Inok, Fischer, Susan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2014
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253556/
https://ncbi.nlm.nih.gov/pubmed/25034079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.06.013
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