The tumor promoting activity of the EP4 receptor for prostaglandin E(2) in murine skin

To determine whether the EP4 receptor for prostaglandin E(2) (PGE(2)) contributes to the tumor promoting activity of PGs in murine skin, EP4 over‐expressing mice (BK5.EP4) were generated and subjected carcinogenesis protocols. An initiation/promotion protocol resulted in 25‐fold more squamous cell c...

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Foilsithe in:Mol Oncol
Main Authors: Simper, Melissa S., Rundhaug, Joyce E., Mikulec, Carol, Bowen, Rebecca, Shen, Jianjun, Lu, Yue, Lin, Kevin, Surh, Inok, Fischer, Susan M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2014
Ábhair:
Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253556/
https://ncbi.nlm.nih.gov/pubmed/25034079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.06.013
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