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The EP1 receptor for prostaglandin E2 promotes the development and progression of malignant murine skin tumors
High levels of prostaglandin E2 (PGE2) synthesis resulting from the upregulation of COX-2 has been shown to be critical for the development of non-melanoma skin tumors. This effect of PGE2 is likely mediated by one or more of its 4 G-protein coupled membrane receptors, EP1–4. A previous study showed...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3270117/ https://ncbi.nlm.nih.gov/pubmed/21739481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20820 |
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