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Exploiting cell metabolism for biocatalytic whole-cell transamination by recombinant Saccharomyces cerevisiae

The potential of Saccharomyces cerevisiae for biocatalytic whole-cell transamination was investigated using the kinetic resolution of racemic 1-phenylethylamine (1-PEA) to (R)-1-PEA as a model reaction. As native yeast do not possess any ω-transaminase activity for the reaction, a recombinant yeast...

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Detalhes bibliográficos
Publicado no:Appl Microbiol Biotechnol
Main Authors: Weber, Nora, Gorwa-Grauslund, Marie, Carlquist, Magnus
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253539/
https://ncbi.nlm.nih.gov/pubmed/24557569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-014-5576-z
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