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Improvement of whole-cell transamination with Saccharomyces cerevisiae using metabolic engineering and cell pre-adaptation
BACKGROUND: Whole-cell biocatalysis based on metabolically active baker’s yeast with engineered transamination activity can be used to generate molecules carrying a chiral amine moiety. A prerequisite is though to express efficient ω-transaminases and to reach sufficient intracellular precursor leve...
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| Publicat a: | Microb Cell Fact |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5209827/ https://ncbi.nlm.nih.gov/pubmed/28049528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0615-3 |
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