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Improvement of whole-cell transamination with Saccharomyces cerevisiae using metabolic engineering and cell pre-adaptation

BACKGROUND: Whole-cell biocatalysis based on metabolically active baker’s yeast with engineered transamination activity can be used to generate molecules carrying a chiral amine moiety. A prerequisite is though to express efficient ω-transaminases and to reach sufficient intracellular precursor leve...

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Bibliografiset tiedot
Julkaisussa:Microb Cell Fact
Päätekijät: Weber, Nora, Gorwa-Grauslund, Marie, Carlquist, Magnus
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209827/
https://ncbi.nlm.nih.gov/pubmed/28049528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0615-3
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