Nonenzymatic glycation of human lens crystallin. Effect of aging and diabetes mellitus.
We have examined the nonenzymatic glycation of human lens crystallin, an extremely long-lived protein, from 16 normal human ocular lenses 0.2-99 yr of age, and from 11 diabetic lenses 52-82-yr-old. The glucitol-lysine (Glc-Lys) content of soluble and insoluble crystallin was determined after reducti...
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| Udgivet i: | J Clin Invest |
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| Principais autores: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1984
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425353/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6438156/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111592 |
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