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Combining targeted drugs to overcome and prevent resistance of solid cancers with some stem-like cell features

Treatment resistance significantly inhibits the efficiency of targeted cancer therapies in drug-sensitive genotypes. In the current work, we studied mechanisms for rapidly occurring, adaptive resistance in targeted therapy-sensitive lung, breast, and melanoma cancer cell lines. The results show that...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Jokinen, Elina, Laurila, Niina, Koivunen, Peppi, Koivunen, Jussi P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253435/
https://ncbi.nlm.nih.gov/pubmed/25238228
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