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CRISPR/Cas9 for overcoming drug resistance in solid tumors

OBJECTIVES: In this review, we focus on the application of clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR associated nuclease 9 (Cas9), as a powerful genome editing system, in the identification of resistance mechanisms and in overcoming drug resistance in the most frequen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Daru
Prif Awduron: Saber, Ali, Liu, Bin, Ebrahimi, Pirooz, Haisma, Hidde J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer International Publishing 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214581/
https://ncbi.nlm.nih.gov/pubmed/30666557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40199-019-00240-z
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