Mutational analysis of genes coding for cell surface proteins in colorectal cancer cell lines reveal novel altered pathways, druggable mutations and mutated epitopes for targeted therapy

We carried out a mutational analysis of 3,594 genes coding for cell surface proteins (Surfaceome) in 23 colorectal cancer cell lines, searching for new altered pathways, druggable mutations and mutated epitopes for targeted therapy in colorectal cancer. A total of 3,944 somatic non-synonymous substi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Donnard, Elisa, Asprino, Paula F., Correa, Bruna R., Bettoni, Fabiana, Koyama, Fernanda C., Navarro, Fabio C.P., Perez, Rodrigo O., Mariadason, John, Sieber, Oliver M., Strausberg, Robert L., Simpson, Andrew J.G., Jardim, Denis L.F., Reis, Luiz Fernando L., Parmigiani, Raphael B., Galante, Pedro A.F., Camargo, Anamaria A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253428/
https://ncbi.nlm.nih.gov/pubmed/25193853
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