Targeting tyrosine-kinases and estrogen receptor abrogates resistance to endocrine therapy in breast cancer

Despite numerous therapies that effectively inhibit estrogen signaling in breast cancer, a significant proportion of patients with estrogen receptor (ER)-positive malignancy will succumb to their disease. Herein we demonstrate that long-term estrogen deprivation (LTED) therapy among ER-positive brea...

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Udgivet i:Oncotarget
Main Authors: Liu, Shuying, Meng, Xiaolong, Chen, Huiqin, Liu, Wenbin, Miller, Todd, Murph, Mandi, Lu, Yiling, Zhang, Fan, Gagea, Mihai, Arteaga, Carlos L., Mills, Gordon B., Meric-Bernstam, Funda, González-Angulo, Ana M.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253418/
https://ncbi.nlm.nih.gov/pubmed/24979294
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