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Metformin: A therapeutic opportunity in breast cancer

Two important, related pathways are involved in cancer growth. The insulin/insulin-like growth factor-1 (IGF1) signaling pathway, which is activated when nutrients are available, and the adenosine mono-phosphateactivated protein kinase (AMPK) pathway, activated when cells are starved for carbohydrat...

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Detalhes bibliográficos
Main Authors: Gonzalez-Angulo, Ana M., Meric-Bernstam, Funda
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840206/
https://ncbi.nlm.nih.gov/pubmed/20215559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1805
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