Outcomes of patients with advanced cancer and KRAS mutations in phase I clinical trials

BACKGROUND: KRAS mutation is common in human cancer. We assessed the clinical factors, including type of KRAS mutation and treatment, of patients with advanced cancer and tumor KRAS mutations and their association with treatment outcomes. METHODS: Patients referred to the Phase I Clinic for treatmen...

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Pubblicato in:Oncotarget
Autori principali: Said, Rabih, Ye, Yang, Falchook, Gerald Steven, Janku, Filip, Naing, Aung, Zinner, Ralph, Blumenschein, George R., Fu, Siqing, Hong, David S., Piha-Paul, Sarina Anne, Wheler, Jennifer J., Kurzrock, Razelle, Palmer, Gary A., Aldape, Kenneth, Hess, Kenneth R., Tsimberidou, Apostolia Maria
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2014
Soggetti:
Clinical Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253408/
https://ncbi.nlm.nih.gov/pubmed/25313136
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