Outcomes of patients with advanced cancer and KRAS mutations in phase I clinical trials

BACKGROUND: KRAS mutation is common in human cancer. We assessed the clinical factors, including type of KRAS mutation and treatment, of patients with advanced cancer and tumor KRAS mutations and their association with treatment outcomes. METHODS: Patients referred to the Phase I Clinic for treatmen...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Said, Rabih, Ye, Yang, Falchook, Gerald Steven, Janku, Filip, Naing, Aung, Zinner, Ralph, Blumenschein, George R., Fu, Siqing, Hong, David S., Piha-Paul, Sarina Anne, Wheler, Jennifer J., Kurzrock, Razelle, Palmer, Gary A., Aldape, Kenneth, Hess, Kenneth R., Tsimberidou, Apostolia Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Clinical Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253408/
https://ncbi.nlm.nih.gov/pubmed/25313136
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