Insulin receptor degradation is accelerated in cultured lymphocytes from patients with genetic syndromes of extreme insulin resistance.

Previous studies of the insulin receptor in disease states have utilized primarily techniques of equilibrium binding and, to a limited extent structural, analysis. Though techniques have been developed to study receptor degradation in normal cells, they have not been applied to disease states. In th...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	McElduff, A, Hedo, J A, Taylor, S I, Roth, J, Gorden, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1984
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425304/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6480829/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111547
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