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Insulin receptor degradation is accelerated in cultured lymphocytes from patients with genetic syndromes of extreme insulin resistance.

Previous studies of the insulin receptor in disease states have utilized primarily techniques of equilibrium binding and, to a limited extent structural, analysis. Though techniques have been developed to study receptor degradation in normal cells, they have not been applied to disease states. In th...

詳細記述

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書誌詳細
出版年:J Clin Invest
主要な著者: McElduff, A, Hedo, J A, Taylor, S I, Roth, J, Gorden, P
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 1984
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425304/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6480829/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111547
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