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Thyroid Hormone-dependent Epigenetic Suppression of Herpes Simplex Virus-1 Gene Expression and Viral Replication in Differentiated Neuroendocrine Cells

A global HSV-1 gene repression occurs during latency in sensory neurons where most viral gene transcriptions are suppressed. The molecular mechanisms of gene silencing and how stress factors trigger the reactivation are not well understood. Thyroid hormones are known to be altered due to stress, and...

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Detalhes bibliográficos
Publicado no:J Neurol Sci
Main Authors: Figliozzi, Robert W., Chen, Feng, Balish, Matthew, Ajavon, Amakoe, Hsia, S. Victor
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252976/
https://ncbi.nlm.nih.gov/pubmed/25175854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2014.08.017
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