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Thyroid Hormone-dependent Epigenetic Suppression of Herpes Simplex Virus-1 Gene Expression and Viral Replication in Differentiated Neuroendocrine Cells

A global HSV-1 gene repression occurs during latency in sensory neurons where most viral gene transcriptions are suppressed. The molecular mechanisms of gene silencing and how stress factors trigger the reactivation are not well understood. Thyroid hormones are known to be altered due to stress, and...

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Pubblicato in:J Neurol Sci
Autori principali: Figliozzi, Robert W., Chen, Feng, Balish, Matthew, Ajavon, Amakoe, Hsia, S. Victor
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252976/
https://ncbi.nlm.nih.gov/pubmed/25175854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2014.08.017
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